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The 5-year overall survival (OS), lung cancer-specific survival, and recurrence-free survival rates for the high/low post-PNI groups were 87.4%/58.4% (P less then 0.001), 92.0%/74.8% (P = 0.001), and 80.5%/55.3% (P less then 0.001). respectively. Multivariate analysis showed that the post-PNI was a significant prognostic factor (P less then 0.001). We further revealed the equivalent OS with "low pre-PNI and high post-PNI" patients or "high pre-PNI and high post-PNI" patients. CONCLUSIONS Post-PNI status was a significant prognostic