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42-0.92, p=0.016) and overall survival (hazard ratio 0.57, 95% confidence interval 0.37-0.88, p=0.011) than patients with non-virus-related ICC. Cox proportional hazard analysis showed that HCV-related ICC offered a worse prognosis than non-virus-related ICC. HCV infection increases the risk of recurrence and worsens overall survival in patients after curative resection for MF and combined MF+PI type ICC. HCV infection increases the risk of recurrence and worsens overall survival in patients after curative resection for MF and combined MF + PI type ICC. The