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There is ambiguity concerning the mechanisms by which syrinx formation and dilation happen. Our study aimed to understand how ependymal cells lining the central canal contribute to syrinx prevention and canal dilation reduction. In order to determine the involvement of ependymal cells in the widening of the central canal, we examined 78 Sprague-Dawley (SD) rats exhibiting syringomyelia. A study of ependymal cell activation in 54 syringomyelia rat models was conducted us
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