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For the Incremental group, a decrease in RKF was recorded, reaching a value of 79.32 mL/min/1.73 m². At the outset, the rate was 32.29 mL/min/173 m. Following the twenty-four-month period, Within the full-dose PD group, the 0001 data point revealed a creatinine clearance rate of 73.27 mL/min per 1.73 square meters. In the initial state, the flow rate recorded 34 mL/minute/173 square meters. T