https://www.selleckchem.com/pr....oducts/ziritaxestat.
PURPOSE Lung cancer is one of the deadly diseases with limited treatment options available. The main aim of the current study was to investigate the antitumor effects of levopimaric acid - a naturally occurring diterpene, against cisplatin-resistant non-small cell lung carcinoma cells A-549 and normal MRC5 cells. Effects of levopimaric acid on autophagy, reactive oxygen species (ROS), apoptosis and ERK/MAPK signalling pathways were also investigated in the current study. METHODS Proliferation rate was monitored by MTS assay. Apopto