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Although histopathology remains in the first line of the diagnosis of pituitary pathology, immunohistochemistry and molecular biology are currently in charge of providing a more accurate characterisation of tumours in this field. A systematic review of the literature was performed, using the PubMed and SCOPUS databases, with terms that included transcription factors involved in the development of pituitary tumours T-PIT, PIT-1, and SF-1. The results showed different perspectives, but the evidence is in favour of a multifold immunohistochem
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