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Extra-renal SLE and lupus nephritis were assessed for efficacy and safety of new biologics in recent phase II randomized controlled trials. Six trials of new drugs produced encouraging data, showing enhancements in a range of clinical and serological outcomes. Successfully investigated has been the combination of B-cell depletion and anti-BLyS treatment strategies. Malnutrition, encompassing both over- and under-nutrition, in the Peruvian Amazon, results in increased chronic dise