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The aim of this study to determine maternal adiponectin and leptin levels as biomarkers of pre-eclampsia and compare adiponectin and leptin ratio. This is a prospective study. The enrolled women were divided into two groups first, study group ( = 6 comprised of women diagnosed with pre-eclampsia and second, control group ( = 6 comprised of age- and gestation-matched normotensive and nonproteinuric women. Maternal serum adiponectin and leptin levels and their ratio were compared in pre-eclamptic (study group) and normotensive (contro