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[This corrects the article DOI 10.1371/journal.pone.0216859.].BACKGROUND Human papillomavirus (HPV) infection is one of the most common ****ually transmitted infections. However, only a small percentage of high-risk (HR) HPV infections progress to cervical precancer and cancer. In this study, we investigated the role of the cervicovaginal microbiome (CVM) in the natural history of HR-HPV. METHODS This study was nested within the placebo arm of the Costa Rica HPV Vaccine Trial that included women aged 18-25 years of age. Cervical samples f