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43 [95%CI=1.24 to 3.61]). Stimulants were the only treatment superior to control (SMD=-1.03 [95%CI=-1.6 to -0.47]). Methylphenidate was the most effective pharmacotherapy. Sertraline appears effective for prevention. The efficacy of psychological interventions is unclear. TMS as a combination therapy appears promising. Heterogeneity of study populations and dearth of evidence means results should be interpreted cautiously. Methylphenidate was the most effective pharmacotherapy. Sertraline appears effective for prevention. The efficacy