https://www.selleckchem.com/products/PD-98059.html
BACKGROUND AND PURPOSE Evidence indicates that the entire kallikrein-kinin system is present in the skin, and it is thought to exert a relevant role in cutaneous diseases, including psoriasis. Thus, the present study was designed to evaluate the relevance of kinin receptors in the development and progression of a psoriasis mice model. EXPERIMENTAL APPROACH Kinin B1 and B2 receptor knockout mice as well as C57BL/6 wild type (WT) mice treated with kinin receptor antagonists (SSR240612C or FR173657) were submitted to the Imiquimod (IMQ)-i
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