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Investigating the clinical effects of pre-treatment tumor encirclement of the esophageal wall in patients with locally advanced esophageal squamous cell carcinoma who underwent curative resection after neoadjuvant chemotherapy. Neoadjuvant chemotherapy followed by curative resection was administered to 96 patients with cStage IB-III esophageal squamous cell carcinoma. Patients were subsequently classified based on tumor location