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Overall survival and indices of disease progression will be measured as the secondary outcomes. Ethical approval has been obtained from the ethics committee of Peking University Third Hospital (M2019388). Informed written consent will be obtained from each participant. Dissemination of the study protocol and data will take place primarily through a specially designed online data system (http//www.chalsr.net/). The collective results of the study will be published in peer-reviewed journals and shared in scientific presentations. NCT04328
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