https://nvp231activator.com/un....der-the-radar-optics
Novel PDT agents, Ir(III)-COUPY conjugates, were formulated by leveraging the beneficial attributes of COUPY fluorophores and cyclometalated Ir(III) complexes, with the ultimate goal of deciphering structure-activity relationships. Significant changes to the coumarin structure profoundly affected the photophysical properties and the conjugates' cellular uptake. Green light irradiation caused substantial phototoxicity in Ir(III)-COUPY conjugates, arising from photo-induced reactive oxygen species (ROS