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ts than in those with GA. These differences did not influence clinical outcome. CI was maintained near baseline values throughout the procedure during US-RA, whereas a significant decrease in CI values was observed during CEA under GA. Near-infrared refracted spectroscopy values, reflecting blood flow in small vessels, were higher in US-RA patients than in those with GA. These differences did not influence clinical outcome. The concept of frailty has been proposed to capture the vulnerability resulting from aging and has been implemented for the pre