https://glytreceptor.com/index.....php/national-differ
GUN4 is hypothesized to offer protection by its interaction with linear tetrapyrroles, including bilins. Our investigation into the origins of bilin binding in GUN4 utilizes both comparative phylogenetic analysis and biochemical validation of a conserved bilin-binding motif. Our findings suggest that GUN4 proteins, which bind bilin, emerged early in cyanobacteria's evolutionary history, signifying an ancient adaptation to sustain chlorophyll synthesis under the conc
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