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016)] in males, but only changes in MVPA in females [β -0.035 (95% CI -0.058; -0.011)]. In analyses of change over time, males who improved MVPA by 20-30 min per day showed significant improvements in cardiometabolic health over 4 yr. The magnitude of association was slightly stronger for MVPA in 10-min bouts than for MVPA accumulated in bouts of 1-min, especially in females. MVPA is an important predictor of cardiometabolic health in early adulthood. Strategies to prevent declines in MVPA at this life stage are required to prevent det