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Pt-based catalysts with core@shell structures are widely used in alcohol oxidations due to their excellent catalytic performance. In this work, we synthesized a series of core@shell PtAuAg@PtAg hollow nanodendrites (HNDs) with different compositions by a simple seed-mediated method. The PtAuAg@PtAg HNDs with a hollow core and dendritic shell exhibit excellent catalytic performance for ethylene glycol oxidation reaction (EGOR) and methanol oxidation reaction (MOR). Among these, Pt38Au29Ag33 HNDs have the highest mass activity (12364.0 mA