https://sb431542inhibitor.com/....coming-from-collecti
The deletion of Acot12 causes an overproduction of LPA, which activates LPA receptors (LPARs) linked to G12/13 proteins. This activation cascade leads to decreased YAP phosphorylation, enabling its nuclear accumulation and subsequent transcriptional function. These findings suggest a protective mechanism for Acot12 in the suppression of hepatocarcinogenesis, w
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