https://www.selleckchem.com/products/rki-1447.html
https://www.selleckchem.com/products/rki-1447.html
Force-mediated molecule discharge through double system hydrogels. We investigate selection of critical boundary functions for testing the hypotheses of two time-to-event outcomes as both primary endpoints or a primary and a secondary endpoint in group-sequential clinical trials, where (1) the effect sizes of endpoints are unequal, or (2) one endpoint is for short-term evaluation and the other for long-term evaluation. Bonferroni-Holm and fixed-sequence procedures are considered.