https://www.selleckchem.com/pr....oducts/rgd-arg-gly-a
Among 22 NICUs, 457 infants were enrolled; gestation 23 to 41 (median 33) weeks and birth weight 595 to 4802 (median 196 grams. In total, 230 infants were randomly assigned to aerosol; 225 received 334 treatments, starting at a median of 5 hours. The rates of intubation for surfactant instillation were 26% in the aerosol group and 50% in the usual care group ( .0001). Respiratory outcomes up to 28 days of age were no different. In newborns with early, mild to moderate respiratory distress, aerosolized calfactant