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The physiological iron balance within the mother, placenta, and developing fetus is examined in this review, along with the consequential perturbations in iron homeostasis that characterize pathological pregnancies. Building upon mechanistic regulatory systems elucidated from animal models, we explore their potential application to the human pregnancy process. The Annual Review of Nutrition, Volume 43, is expected to be published online in the month of August 2023. For the most up-to-
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