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ared with healthy controls. Patients show a diminished competency to consent and increased emotional blunting, while motivation is not compromised. Cerebrovascular comorbidity in KS forms a high risk for emotional blunting. The results of this study suggest that apathy is a severe problem in KS. More attention in both the literature and clinical practice would benefit this complex patient population.Standard metabolic rate (SMR), defined as the minimal energy expenditure required for self-maintenance, is a key physiological trait. Few s

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A significant difference was noted regarding the need for additional doses; 10% of patients in the D-K group needed one extra dose, and 5% needed two extra doses, compared to 25% and 20% in the P-K group, respectively (p=0.001). The P-K group showed less post-procedure nausea and vomiting. No statistically significant difference between both groups regarding endoscopist satisfaction. The P-K combination was associated with a shorter recovery time in pediatric upper gastrointestinal endoscopy, while the D-K combination showed

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This gives excellent clinical and radiological results. Osteoarticular tuberculosis (T constitutes 1-3 % of cases and about 10% of osteoarticular TB affects the foot and ankle. In foot, TB calcaneus is the most commonly affected bone. A 21-year-old male presented with pain, swelling in the right heel for 5 months and difficulty in walking for 2 months. Plain X-ray (axial) view of calcaneus showed a lytic lesion in calcaneus. Biopsy was done under local anaesthesia and histologic examination revealed a characteristic granuloma, caseous

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Common genetic variants interact with environmental factors to impact risk of heritable diseases. A notable example of this is a single-nucleotide variant in the Solute Carrier Family 39 Member 8 (SLC39A8) gene encoding the missense variant A391T, which is associated with a variety of traits ranging from Parkinson's disease and neuropsychiatric disease to cardiovascular and metabolic diseases and Crohn's disease. The remarkable extent of pleiotropy exhibited by SLC39A8 A391T raises key questions regarding how a

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The Ultimate Guide to Coffee Machine Sales: Finding Your Perfect Brew Coffee is more than just a drink; for many, it is a routine and a passion. of an excellent cup of coffee has led to an expanding market for coffee machines. Sales of coffee machines have surged recently due to the growing appreciation for specialty brews and home developing benefits. This article aims to inform purchasers about the myriad alternatives available in coffee machine sales, co

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Dietary exposure is a major cause of pesticide bioaccumulation in herbivores. However, various types of natural conditions affect the structure of the complicated herbivores' diets, making it difficult to assess their exposure to pesticides. In this study, to evaluate the role of pesticides in the terrestrial food web, a dynamic hybrid dietary model was developed for North American white-tailed deer (or whitetails), which integrates different plant types and the digestibility of deer's foods. Moreover, an equivalent season approach was

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Automatic identification of consistently defined body regions in medical images is vital in many applications. In this paper, we describe a method to automatically demarcate the superior and inferior boundaries for neck, thorax, abdomen, and pelvis body regions in computed tomography (CT) images. For any three-dimensional (3D) CT image I, following precise anatomic definitions, we denote the superior and inferior axial boundary slices of the neck, thorax, abdomen, and pelvis body regions by NS(I), NI(I), TS(I), TI(I), AS(I)

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Overall, we demonstrated that the ratio of polar axis length to equatorial axial length, pollen characteristics at the polar view, the colpus morphology, and the surface ornamentation of pollen grains of genus Veratrum have important systematic significance in identification and delimitation of species. © 2020 Wiley Periodicals, Inc.WHAT IS KNOWN AND OBJECTIVE Vitamin K deficiency is known to cause impaired coagulation. We report a case of marked prolongation of the prothrombin time-international normalized ratio (PT-INR) associated w

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All animals use external cues from the environment to accurately time life-history events. How the brain decodes environmental stimuli to effect changes in physiology and behavior, however, is poorly understood, particularly with regard to supplementary environmental cues such as temperature. We asked if low-temperature dormancy alters the synthesis and/or release of gonadotropin-releasing hormone (GnRH). We used the well-studied red-sided garter snake (Thamnophis sirtalis) for this study, as low-temperature exposure is both necessary and suf

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Alport syndrome (AS) is a hereditary glomerular nephritis caused by mutation in one of the type IV collagen genes α3/α4/α5 that encode the heterotrimer COL4A3/4/5. Failure to form a heterotrimer due to mutation leads to the dysfunction of the glomerular basement membrane, and end-stage renal disease. Previous reports have suggested the involvement of the receptor tyrosine kinase discoidin domain receptor (DDR) 1 in the progression of AS pathology. However, due to the similarity between DDR1 and DDR2, the role of DDR2 in AS pathology is unclea