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Following active muscle shortening, steady-state isometric force is less than a purely isometric contraction at the same muscle length and level of activation; this is known as residual force depression (rFD). It is unknown whether rFD at the single muscle fiber level can be modified via training. Here we investigated whether rFD in single muscle fibers is modifiable through downhill and uphill running in the extensor digitorum longus (EDL) and soleus (SOL) muscles in rats. Rats were run uphill or downhill 5 days/week for 4 weeks. Afte

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The mycotoxin zearalenone (ZEN) is a frequent contaminant of animal feed and is well known for its estrogenic effects in animals. Cattle are considered less sensitive to ZEN than pigs. However, ZEN has previously been shown to be converted to the highly estrogenic metabolite α-zearalenol (α-ZEL) in rumen fluid in vitro. Here, we investigate the metabolism of ZEN in the reticulorumen of dairy cows. To this end, rumen-fistulated non-lactating Holstein Friesian cows (n = 4) received a one-time oral dose of ZEN (5 mg ZEN in 500 g concentrat

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현재 사회에서는 스트레스와 압박이 일상적인 문제로 자리 잡고 있습니다. 빠듯한 일상 속에서 신체와 정신의 안정을 찾기란 쉽지 않죠. 이런 우리에게 가장 도움이 되는 것이 마사지입니다. 특별히 출장 마사지, 출장 스웨디시, 홈타인 는 집이나 안락하게 받을 수 있어 많은 분들에게 인기를 끌고 있습니다. 마사지의 안락함은 단순히疲れを 퇴치하는 것에만 국한되지 않습니다. 몸의 긴장을 완화해주며, 따라서 마음의 평화를 찾음에 있어서도 많은 도움을 줍니다. 이번 날에는 육체와 정신이 서로 풀리는 마사지의 세계를 제안하며, 그러므로 여러분이 체험할 수 있는 편안한 느낌을 공유해 보려고 합니다. 마사지 서비스의 이점 출장안마는 바쁜 일상 속에서 안락함과 쉼을 제공하는 우수한 대안입니다. 주목할 점은, 자택이나 사무실 등 친숙한 환경에서 이루어지는 출장안마는 이동 중의 스트레스를 줄여주고, 심리적 편안함을 더해줍니다. 이렇게 여러분의 체계은 편안함을 느끼고, 긴장을 풀며 진정한 안식을 얻을 수 있습니다. 전문적인 마사지사가 현장에서 방문하여

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013). Significant reverse correlations were observed between the perception of menstruation as a debilitating, bothersome, and predictable event with a total score of FSFI and all subscales except lubrication (p = 0.001). In contrast, there was a positive relationship between denial of any effects of menstruation with total FSFI and all its sub-scores except lubrication (p = 0.001). This study highlighted the role of masculinity and androgyny gender role stereotypes and menstrual attitude in the ****ual function of hetero****ual women. Future studies are need

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This work contributes to expand the community knowledge regarding the molecular and clinical landscapes of b-GAL deficiency for a better patient management. This study reports one of the largest series of b-GAL deficiency with an integrative patient stratification combining molecular and clinical features. This work contributes to expand the community knowledge regarding the molecular and clinical landscapes of b-GAL deficiency for a better patient management. Haemorrhages of brainstem cavernous malformations (CMs) can lead to neurologi

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Residents of a large area of the Veneto Region (North-Eastern Italy) were exposed for decades to drinking water contaminated by perfluoroalkyl substances (PFAS). PFAS have been consistently associated with raised serum lipids, mainly in cross-sectional studies and in background exposure contexts, but the shape of the dose-response relationships has been poorly investigated. The objectives of our study were to evaluate the association between serum PFAS and serum lipids and their dose-response patterns in a large exposed population. A c

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2% in 2009 to 20.7% in 2018. Most cited articles were published in high impact journals outside the scope of diagnostic imaging. Most influential topics included technical innovations within imaging modalities. MRI replaced conventional radiography and CT as the imaging technique of choice in imaging research. Most cited articles were published in high impact journals outside the scope of diagnostic imaging. Most influential topics included technical innovations within imaging modalities. MRI replaced conventional r

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출장을 하면서 일에 전념해야 해서 편안한 휴식 시간을 가지기 어려운 경우가 많습니다. 그러나 그만큼 우리의 몸과 마음이 요구하는 특별한 배려가 필요합니다. 라는 대안은 이와 같은 상황에서 프리미엄 힐링을 경험할 수 있는 완벽한 방법입니다. 빠듯한 일정 속에서도 출장마사지를 이용하여 지친 하루의 긴장을 완화하고 새로운 에너지를 얻을 수 있습니다. 출장마사지 서비스는 전문 테라피스트들이 출장지를 찾아와 제공되므로, 내가 원하는 시간에 언제든지 맞춤형 서비스를 받을 수 있습니다. 그로 인해 업무 효율성을 높일 수 있는 시간을 효율적으로 활용할 수 있게 되는 것입니다. 출장 마사지를의 장점 출장 중에는 여러 사람들과의 만남과 일로 인하여 스트레스와 피로가 쌓이기 쉽습니다. 이런 상황에서 마사지 경험를 선택하면 신체와 마음의 긴장을 완화하여 피로를 풀 수 있는 기회를 제공합니다. 숙련된 마사지사가 하는 출장 마사지는 출장의 지친 일상 속에서도 고급스럽고 편안한 경험을 선

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cacy of Apremilast for the treatment of immunotherapy-induced psoriasis in metastatic melanoma.Lung cancer is the most common malignant tumor with the highest mortality, and about 84% are non-small cell lung cancer (NSCLC). However, only a small proportion of patients with newly diagnosed lung tumors can receive curative surgery and have a high risk of postoperative recurrence. At present, there are many perioperative treatment methods being continuously explored, such as chemotherapy and targeted therapy, continuously enriching the con