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This article is categorized under RNA Export and Localization RNA Localization RNA Evolution and Genomics Computational Analyses of RNA RNA Methods RNA Analyses in Cells. © 2020 The Authors. WIREs RNA published by Wiley Periodicals, Inc.The Waterloo Farm lagerstätte in South Africa provides a uniquely well-preserved record of a Latest Devonian estuarine ecosystem. Ecological evidence from it is reviewed, contextualised, and compared with that available from the analogous Swartvlei estuarine lake, with

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Men who have **** with men (MSM) are one of the key populations driving HIV/AIDS epidemic globally. To date, MSM is the only population in Ukraine where the prevalence and incidence of HIV is increasing. As HIV-positive MSM might feel uncomfortable to report homo****ual intercourses as a possible mode of transmission (MoT) of HIV, they prefer being registered as patients with hetero****ual or non-defined MoT. This study aimed to calculate the proportion of misclassified MoT among HIV-positive MSM registered in Lviv oblast, Ukrain

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space availability and sewage treatment capacity. In addition, the optimized method proposed in this paper could reflect the pollutant accumulation characteristics of the catchment. It not only reduce the total cost of the water environment management but also effectively reduce the impact of non-point source pollution on urban water system, and could be more widely used in other areas and PPP projects.A series of environmental protective policies have been taken recently in the Pearl River Estuary (PRE) to alleviate water pollution; however, their influenc

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Insurance is a crucial aspect of monetary planning that often gets overlooked until an sudden event happens. Many persons view it as just one more expense, but the real purpose of insurance goes above just covering regular premiums. It exists as a safety net, designed to shield people and families from the financial strains that can occur from accidents, natural disasters, health issues, and more. Understanding this purpose can empower individuals to make knowledgeable decisions regarding their insurance options. In

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College students with attention deficit/hyperactivity disorder (ADHD) are at increased risk for numerous educational and psychosocial difficulties. This study reports findings from a large, multisite randomized controlled trial examining the efficacy of a treatment for this population, known as ACCESS-Accessing Campus Connections and Empowering Student Success. ACCESS is a cognitive-behavioral therapy program delivered via group treatment and individual mentoring across two semesters. A total of 250 student

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The fragile X mental retardation protein (FMRP), an RNA-binding protein, regulates cocaine-induced neuronal plasticity and is critical for the normal development of drug-induced locomotor sensitization, as well as reward-related learning in the conditioned place preference assay. However, it is unknown whether FMRP impacts behaviors that are used to more closely model substance use disorders. Utilizing a cocaine intravenous self-administration (IVSA) assay in Fmr1 knockout (KO) and wild-type (WT) littermate mice, we find that, despite no

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© 2020 Tehran University of Medical Sciences.Introduction Mesenteric cysts are rare benign intra-abdominal vesicles with various clinical presentations. They almost located in the mesentery of the small intestine. The selective therapeutic method is complete surgical excision, however more than half need resection and bowel anastomosis. Case presentation Here, we presented a 5-year-old girl with a huge mesenteric cyst (15×14cm2) mesenteric cyst that was excised surgically., which the diagnosis confirmed by computed tomography scan and m

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6months. By multivariable analysis, a Gleason grade of 5 and bone metastasis lesion count ≥ 4 were found to be significantly associated with CRPC-free survival (hazard ratio (HR), 1.45; 95% confidence interval (CI), 1.01-2.07) and (HR 2.02; 95% CI 1.39-2.92) and overall survival (HR 1.67 95%; CI 1.16-2.42) and (HR 1.67 95%; CI 1.16-2.41). Bone metastases ≥ 4 and a Gleason grade 5 are independent prognostic factors for CRPC-free and overall survival in mHSPC. A Gleason grade 5 is therefore a new prognostic indicator in mHSPC. Bone metast