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In the second aspect (prompting during a conversation), a robot encourages eye contact and suggests possible answers, e.g., during free conversation with a peer. In the third aspect (teaching, entertainment), the robot could play with autistic children in games supporting the development of joint attention. These types of games stimulate the development of motor skills and orientation in the body schema. In future work, a validation test would be desirable to check whether children with ASD are able to do the same with a real person by

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Rich information is provided by 360-degree videos. However, non-uniform geometric deformation caused by sphere-to-plane projection significantly decreases tracking accuracy of existing trackers, and the huge amount of data makes it difficult to achieve real-time tracking. #link# Thus, this paper proposes a Siamese networks-based people tracker using template update for 360-degree equi-angular cubemap (EAC) format videos. Face stitching overcomes the problem of content discontinuity of the EAC format and avoids raising new geometric def

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Lankacidins are a class of polyketide natural products isolated from Streptomyces spp. that show promising antimicrobial activity. Owing to their complex molecular architectures and chemical instability, structural assignment and derivatization of lankacidins are challenging tasks. Herein we describe three fully synthetic approaches to lankacidins that enable access to new structural variability within the class. We use these routes to systematically generate stereochemical derivatives of both cyclic and acyclic lankacidins. Additio

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Our study suggests that ELII is a promising approach supporting fast temporal query, an important mode of cohort development for Covid-19 studies. To analyse the strains collected during a 1-year survey of ceftazidime-avibactam-resistant KPC-producing Klebsiella pneumoniae, in order to investigate the molecular mechanisms potentially responsible for their resistant phenotype. Clinical KPC-producing K.pneumoniae isolates were collected from 31 patients in six different hospitals in Rome. For eight of the pati

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The pituitary gland, a pivotal player in the body's endocrine system, is the commanding gland. Although the organ is of modest dimensions, many forms of tumors can be found within its structure. The World Health Organization (WHO)'s recent fifth edition revision of their classifications (including the 2021 and 2022 editions, covering Central Nervous System and Endocrine/Neuroendocrine Tumors, respectively), brought about substantial changes to the way pituitary adenomas, the most common pituitary gland tumors, are classified. A significant change in the ca

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Dipeptidyl peptidase 4 (DPP-4) inhibitors exert pleiotropic effects beyond glycemic control. We investigated the renoprotective effects of DPP-4 inhibitors on aging mice mediated by the renin-angiotensin system (RAS). C57BL/6 mice were divided into three groups the two-month-old mice (YM group), the eighteen-month-old mice (AM group) and the eighteen-month-old, linagliptin-treated mice (AM + LIN group). Renal function was improved, based on serum creatinine and cystatin-C levels (p less then 0.05 compared with the AM group for both par

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It has been proven that the treatment window of small cell lung cancer (SCLC) is short, so it is vital to find other possible therapeutic targets. CD39 inhibits natural killer (NK) cells and promotes the occurrence and metastasis of tumors. There has been little research about the role of CD39 in SCLC, so we explored the correlation between CD39 and other surface antigens, and its association with survival in SCLC. This study included 75 patients with SCLC from Shanghai Pulmonary Hospital. After paraffin embedding and sectioning, immunohist