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These findings allow us to demonstrate how SWIM-based correlation network analysis can serve as a useful tool for efficient screening of potentially new disease gene associations. When integrated with an interactome-based network analysis, it not only identifies novel candidate disease genes, but also may offer testable hypotheses by which to elucidate the molecular underpinnings of human disease and reveal commonalities between seemingly unrelated diseases.Motile plant structures such as Mimosa pudica leaves, Impatiens g

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Reducing dietary sodium (salt) intake has been proposed as a population-wide strategy to reduce blood pressure and cardiovascular disease (CVD). The cost-effectiveness of such strategies has hitherto not been investigated in Cameroon. A multicohort multistate life table Markov model was used to evaluate the cost-effectiveness of three population salt reduction strategies mass media campaign, school-based salt education programme and low-sodium salt substitute. A healthcare system perspective was considered and adults alive in

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Systemic lupus erythematosus (SLE) is an inflammatory disease. The sera of SLE patients contain antibodies-abzymes hydrolyzing myelin basic protein (MBP), DNA, nucleotides, and oligosaccharides. The blood of SLE patients contains an increased amount of some specific miRNAs. This study aimed to analyze a possible hydrolysis of eight microRNAs found in the blood of SLE patients with high frequency by blood antibodies-abzymes. Using affinity chromatography of the serum proteins of SLE patients and healthy donors on protein G-Sepharose and fo

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Giant cell arteritis (GCA) is characterized by granulomatous inflammation of large and medium-sized vessels. It is the most common vasculitis among elderly people in Europe and North America. GCA usually presents with ischemic cranial manifestations such as headache, scalp tenderness, visual manifestations, and claudication of the tongue and jaw. Thickness and tenderness of temporal arteries are the most recognizable signs of GCA on physical examination. Laboratory tests usually show raised acute phase reactants. Skin manifestations are u

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The Modern Kitchen: Embracing Built-In Ovens and Microwaves In modern kitchen design, performance and aesthetics play essential roles. Among the key appliances that embody this consistency are built-in ovens and microwaves. These components not only boost the performance of food preparation however likewise contribute to a streamlined, sophisticated kitchen layout. This short article checks out the benefits, functions, and factors to consider of integrating built-in ovens and microwaves