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We evaluated preoperative CA 19-9 levels in patients with resected pancreatic cancer to analyze whether they were predictive of clinical outcomes and could help select patients for additional therapy. We hypothesized that elevated CA 19-9 would be associated with worse pathologic findings and oncologic outcomes. This study assessed 509 patients with non-metastatic pancreatic adenocarcinoma who underwent resection at our institution from 1995-2011 and had preoperative CA 19-9 recorded. No patients received neoadjuvant therapy. C

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Furthermore, ER stress in KCs promoted the polarization of KCs towards the M1 phenotype and increased the expression of TNF- . The increase in KC-derived TNF- triggered the apoptosis of HSCs and the activation of TNF-R1/caspase 8 in vitro, which was consistent with the in vivo results. ER stress in KCs promotes the polarization of these cells towards the M1 phenotype and increases the expression of TNF- . Then, the increase in KC-derived TNF- triggers the apoptosis of HSCs through TNF-R1/caspase 8. ER stress in KC

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This experiment was designed to evaluate the effects of different concentrate crude protein (CP) concentration on performance, metabolism and efficiency of N utilization (ENU) on early-lactation dairy cows grazing intensively managed tropical grass. Thirty cows were used in a ten ****ted 3 × 3 Latin square design. The treatments consisted of three levels of concentrate CP 7.9%, 15.4%, and 20.5% offered at a rate of 1 kg (as-fed basis)/3 kg of milk. The cows fed low and medium CP had negative balance of rumen degradable protein and me

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Urbanization impacts wildlife, yet research has been limited to few taxa. American alligators (Alligator mississippiensis) are apex predators that have received minimal attention within urban areas. We investigated potential effects of urban land use on alligators through surveys of relative alligator abundance in nine tributaries of the lower St. Johns River within Jacksonville, FL. We then explored the potential effects of urban development on alligator spatial distribution and habitat selection at coarse and fine scales. At the coars

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The present research is aimed at clarifying meta-analytically the relation of so-called Dark Triad (DT; i.e., narcissism, Machiavellianism, or psychopathy) traits to factor analytic models covering the basic personality space. Unlike recent meta-analyses that investigated such relations at the bivariate level, we used 2-stage structural equation modeling (TSSEM) meta-analysis to explore the full complexity of structural relations between DT traits and the five-factor model (FFM) and HEXACO dimensions, as well as the higher-order persona

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The Rise of Cheap Coffee Machines: An In-Depth Exploration In a world where coffee culture continues to prosper, the demand for quality brews has heightened considerably. Nevertheless, not everybody can manage to spend lavishly on high-end coffee machines that promise barista-level coffee at home. Go into cheap coffee machines-- a category that has grown tremendously recently. This post looks into the functions, advantages, and factors to consider surrounding affordable coffee machines, helping

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The Ultimate Guide to Buying a Built-In Oven In the realm of modern cooking appliances, built-in ovens stand out for their seamless combination into kitchen cabinetry, aesthetic appeal, and advanced cooking technologies. They offer a myriad of functions and a streamlined style, dealing with both cooking enthusiasts and everyday cooks. Nevertheless, picking built-in oven can be challenging given the plethora of choices readily available in the market. This article works as an extensive guide, highlighting essential factors to

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We aimed to evaluate the prognostic value of neutrophil-to-lymphocyte ratio (NLR) in emergency department (ED) patients with cutaneous adverse drug reactions to identify the severe patients at an early stage. In this retrospective study, patients aged 18 and over who admitted to the ED of a university hospital with the diagnosis of cutaneous adverse drug reaction were included. For included patients, clinical findings and ED admission complete blood count results were recorded. The primary outcome was hospitalization and the se

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The spectral changes due to chlorination of the CuPc molecule were mainly attributed to an increase of the threshold energy of the C atoms bonded to chlorine, and the influence of the change in the PDOS by chlorination was not significantly large.An antimalarial lipopeptide, ikoamide, was isolated from an Okeania sp. marine cyanobacterium. Its gross structure was established by spectroscopic analyses, and the absolute configuration was clarified based on a combination of chiral-phase HPLC analyses, spectroscopic analyses, and derivat

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