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mor in the extremities and no plantar reflex pathology were detected, sensitivity disorders in the hands "the high gloves" and no pelvic disorders were detected. Given the presence and exacerbation of neurological symptoms and cutaneous angiomas, MRI with a contrast agent of the cervical spine was recommended. MR-image of an advanced arteriovenous malformation (AVM) of the cervical spinal cord with signs of gliosis and spinal cord oedema at the C2-C7 level. Endovascular embolization of the AVM in the cervical spinal cord was p

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Total emissions attributed to the study period (including carbon not yet released) is 6.97 ± 1.24 Tg C yr-1. The presented model is based on recent technological advancements in the field of remote sensing to achieve spatially explicit modeling of carbon emissions and uptake associated with land surface changes and post-disturbance landscapes that is compliant with international reporting criteria. Waterborne disease outbreaks associated with recreational waters continue to be reported around the world despite existing microb

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The main goal of peptide-based cancer vaccines is to induce the immune system and activation of effective T cell responses against cancerous cells. Nevertheless, the potency of peptide vaccines is insufficient in most of cases and had limited clinical success. Therefore, the optimization of peptide-based cancer vaccine is essential to achieve powerful therapeutic outcomes. One strategy to enhanced potency of peptide vaccines and induce strong immune responses is the preparation of multi-epitope peptide formulation containing both Th- an

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The basic value of rSO in elderly patients is lower. Age is an important factor that affects the underlying value of rSO . The basic value of rSO2 in elderly patients is lower. Age is an important factor that affects the underlying value of rSO2.Mesenchymal stem cells (MSCs) have the potential to differentiate into neuron-like cells, which may provide a new strategy for the clinical treatment of neurodegenerative diseases such as Parkinson's disease (PD). However, the application of MSCs in the patients is still limited as the reason o

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One diagnosis of cystic fibrosis involves measuring the nasal transepithelial potential difference (NPD) as a complementary technique in the forms of the disease, where the sweat test is non-discriminating. The NPD is measured using solutions with and without chlorides, containing a variety of substances whose activities on nasal mucus membranes are studied or assessed. Among the solutions described in the literature and used in specialized centers, none seems to be best adapted for industrial production for reasons of stability (formul

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The magnitude and consistency of the **** differences in meningococcal disease incidence rates (IR) have not been systematically examined in different age groups, countries and time periods. We obtained national data on meningococcal disease IR by ****, age group and time period, from 10 countries. We used meta-analytic methods to combine the male to female incidence rate ratios (IRRs) by country and year for each age group. Meta-regression analysis was used to assess the contribution of age, country and time period to the variation in t

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To assess the current status of influenza A viruses of swine (IAVs-S) throughout Japan and to investigate how these viruses persisted and evolve on pig farms, we genetically characterized IAVs-S isolated during 2015-2019. Nasal swab samples collected through active surveillance and lung tissue samples collected for diagnosis yielded 424 IAVs-S-comprising 78 H1N1, 331 H1N2, and 15 H3N2 viruses-from farms in sampled 21 prefectures in Japan. Phylogenetic analyses of surface genes revealed that the 1A.1 classical swine H1 lineage has evolve

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051). The SPEED scores negatively correlated with LLT in all patients (r=-0.136, p0.001). Younger patients also had thinner average LLT (p0.001), lower meiboscale (p0.001) and a higher number of expressible meibomian glands (p0.001). Additionally, they had significantly more total blinks (p0.001), incomplete blinks (p0.001), and incomplete blink rate (p=0.006). Manifestations of DED vary with age. In our cohort, younger age patients had more symptoms and blinks, which may have resulted from thinner LLT as the struc

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The decrease in the total Green test score was 55,3 % and 39,9 %, respectively (p  0,0001). Non-drug complex programs with physiotherapy improve carbohydrate metabolism and contribute to the regression of menopausal disorders in women with metabolic syndrome during the menopausal transition. The priority is the simultaneous use of vibration therapy, chromotherapy, melotherapy, aromatherapy and aeroionotherapy. Non-drug complex programs with physiotherapy improve carbohydrate metabolism and contribute to the regression of menop

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Initial quantitative contributions in our research are dedicated to elucidating multiple reaction mechanisms, specifically quasifree knockout, inelastic scattering, and nucleon transfer. It is shown that the processes of inelastic scattering and nucleon transfer, typically overlooked in this energy regime, contribute roughly 50% and 30% to the removal of loosely bound protons and deeply bound neutrons, respectively. Quantitative investigation of single-particle stre