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The aim of the study is to report on epidemiological, clinical, and biochemical characteristics of nonketotic hyperglycinemia (NKH) in Tunisia. Patients diagnosed with NKH in Laboratory of Biochemistry at Rabta hospital (Tunis, Tunisia) between 1999 and 2018 were included. Plasma and cerebrospinal fluid (CSF) free amino acids were assessed by ion exchange chromatography. Diagnosis was based on family history, patient's clinical presentation and course, and increased CSF to plasma glycine ratio. During 20 years, 69 patients were diagnosed

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Buying a Driving License Online: What You Need to Know In today's digital age, many services have actually shifted online, and the procedure of obtaining a driving license is no exception. While the convenience of buying a driving license online might be enticing, it is vital to browse these waters carefully to prevent scams and legal repercussions. This article will offer a thorough summary of the legitimate st

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The Ultimate Guide to Buying Fireplaces Online: What You Need to Know Over the last few years, the pattern of acquiring home appliances and decorative products online has surged, showing a considerable shift in customer habits. One such product gaining popularity in the online marketplace is the fireplace. Whether for aesthetic appeal, atmosphere, or usefulness, a fireplace can change a home. This short arti

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The SARS-CoV-2 pandemic has highlighted existing systemic inequities that adversely affect a variety of communities in the United States. These inequities have a direct and adverse impact on the healthcare of our patient population. While civic engagement has not been cultivated in surgical and anesthesia training, we maintain that it is inherent to the core role of the role of a physician. This is supported by moral imperative, professional responsibility, and a legal obligation. We propose that such civic engagement and social justic

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Virtual clinical trials (VCTs) can be used to evaluate and optimise medical imaging systems. VCTs are based on computer simulations of human anatomy, imaging modalities and image interpretation. OpenVCT is an open-source framework for conducting VCTs of medical imaging, with a particular focus on breast imaging. The aim of this paper was to evaluate the OpenVCT framework in two tasks involving digital breast tomosynthesis (DBT). First, VCTs were used to perform a detailed comparison of virtual and clinical reading studies for the detecti

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Unleashing the Power of Cycle Workout Bikes: A Comprehensive Guide Worldwide of fitness, stationary bicycle have actually long been a staple tool for individuals wanting to enhance their cardiovascular health, burn calories, and build lower body strength. Amongst the various kinds of exercise bikes, cycle workout bikes have actually gotten immense popularity due to their ability to imitate the experience of outdoor cycling. This short article w

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The Rise of Online Fridge Sales: A Comprehensive Guide In the last few years, the appliance market has experienced a considerable change, with a growing pattern towards online sales. Among different devices, refrigerators have actually taken a considerable section of this online marketplace. This article dives into the aspects contributing to the rise of online fridge sales, the benefits of purchasing refrigerators online, and necessary suggestions for consumers aiming to buy a frid

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The Ultimate Guide to Buying a Sale Fridge: Maximize Value and Efficiency When it comes to home devices, the refrigerator plays a pivotal role in our day-to-day lives. It not only preserves food however also helps keep a healthy lifestyle by keeping perishables fresh. Given its importance, discovering the best fridge-- especially during a sale-- can lead to substantial cost savings. explores key factors to consider for acquiring a fridge on sale, important features to search for, and some frequently asked concerns. Why Bu

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7%). After a median follow-up of 11 months (range 2-27 months), median progression-free survival was 9.1 months (95% CI, 5.4 to 12.9 months). Median progression-free survival for patients who were refractory to both lenalidomide and bortezomib versus nonrefractory was 5.5 and 12.6 months, respectively, which was significant statistically ( = .04, hazard ratio, 0.35, 95% CI, 0.28 to 0.97). The median overall survival was not reached. Important toxicities included anemia (28%), neutropenia (16%), pneumonia (16%), and venous thrombosis (5%