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Moreover, we found that interleukin-6 (IL-6)/STAT3 could elevate miR-135b levels and that STAT3 directly bound the promoter of miR-135b; thus, these findings highlight a new positive feedback loop of the IL-6/STAT3/miR-135b/NF-κB signaling in NSCLC and suggest that miR-135b could be a potential therapeutic target for NSCLC.Understanding the role of neuropilin 2 (NRP2) in prostate cancer cells as well as in the bone microenvironment is pivotal in the development of an effective targeted therapy for the treatment of prostate cancer bone m

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Đàn ông từ lâu đã được xem là biểu tượng của sức mạnh, bản lĩnh và sự chở che. Trong từng giai đoạn lịch sử, vai trò, hình ảnh của người đàn ông có thể thay đổi, nhưng những giá trị cốt lõi về trách nhiệm, bản lĩnh và sự kiên định vẫn luôn là nền tảng bền vững. Đàn ông hiện đại – Hơn cả sức mạnh thể chất Ngày nay, khái niệm về đàn ông không chỉ gói gọn trong hình ảnh mạnh mẽ về thể chất mà còn mở rộng ra những giá trị về trí tuệ, cảm xúc và lối sống: Bản lĩnh và trách nhiệm: Là người dám đối mặt với thử thách, biết chịu trách nhiệm với lựa chọn và hành động của mình

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BACKGROUND High incidence of treatable oral conditions has been reported among palliative patients. However, a large proportion of palliative patients lose their ability to communicate their sufferings. Therefore, it may lead to under-reporting of oral conditions among these patients. This review systematically synthesized the published evidence on the presence of oral conditions among palliative patients, the impact, management, and challenges in treating these conditions. METHODS An integrative review was undertaken with defined sea

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Brazilian Registry of Clinical Trials RBR-74SNST.The objective of this article is to analyze the spatial distribution of Hepatitis B vaccine (HBVAC) of pregnant women. This is a cross-sectional study carried with 266 puerperae. The HBVAC record was obtained through the prenatal care booklet. The spatial scanning technique was used to detect a cluster of risk for the presence or absence of an HBVAC record. After this cluster identification, the individual and environmental variables were compared between the Coverage Areas of Basic Health

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Initiating a new business might be an exciting yet daunting journey for any business owner. Among the many decisions you'll need to make, choosing a designated agent is essential for ensuring compliance and upholding a positive standing with your state. designated agent serves as your business's off

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Likewise, place of residence, women's education, religion, and wealth index were also found to be associated with the WHO recommended ANC contacts. Furthermore, the husband's education, division, religion and husband's employment showed significant associations with ANC contacts by qualified doctors. However, Bangladeshi women in general revealed an unsatisfactory level of ANC contacts, the WHO recommended as well as ANC contacts by qualified doctors. In order to improve the situation, it is necessary to follow the most rec

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MSC released extracellular vesicles transporting TGF-beta upregulate Smad Six term and market the particular restoration of neurons throughout spinal-cord wounded subjects. Lactose (LAC) is a disaccharide - major sugar, present in milk and dairy products. LAC content is an important indicator of milk quality and abnormalities in food industries, as well as in human and animal health. The present study reports the development of an innovative imprinted voltammetric sensor for sensit