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The resected group had larger nodule sizes (median 8mm vs. 5mm; P=0.06, whereas the observed group had more main pancreatic duct (MPD) dilation (median 10mm vs. 5mm; P=0.005). In the resected HRS group, only patients with MPD dilation ≥10mm (n=1 had no recurrence but had a favorable prognosis compared with those nodule size ≥5mm (n=45). Large nodule size may be associated with pancreatobiliary subtype and poor prognosis; however, patients with MPD dilation ≥10mm with nodule size 5mm did not require resection. Large nodule size

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