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Agreement was at least moderate overall (kappa ≥ 0.42) for all pre-specified measures and among PWH vs HIV-negative, and African-American vs white sub-groups. Having at least one HbA1c ≥6.5% provided substantial agreement with chart adjudication for prevalent and incident diabetes (kappa = 0.89 and 0.73). Identification of those with diabetes nationally within the VHA can be used in future studies to evaluate treatments, health outcomes, and adjust for diabetes in epidemiologic studies. Our methodology may provide insights for other org

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Obesity is a chronic low-grade inflammatory condition, and β2-adrenergic agonists as well as exercise have been proposed as anti-inflammatory strategies in obesity, so it is critical to accurately determine the effects of β2-adrenergic stimulation, especially when combined with other non-pharmacological therapies. The aim of this investigation was to determine the effect of β2-adrenergic activation on the inflammatory profile and phenotype of macrophages, and whether these effects could be affected by obesity and exercise in this condit

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Though his forearm cephalic vein measured a mere 15mm, his basilic vein presented a more substantial size. He experienced a successful outcome following the RBTAVF procedure. While radiocephalic AVF is often the preferred initial approach, brachiocephalic fistula (BCF) is frequently cited as a suitable alternative in many guidelines. International guidelines should prioritize RBAVF as a secondary vascular access option, alongside B

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Patrons of staff canteens were referred to as "canteen enthusiasts" or "canteen medium-enthusiasts", who are "snack lovers", as well as "food choice-oriented" or "quality-oriented". The results provide the basis for practical implications for owners or managers of staff canteens, part of whose work it is to analyze the needs and expectations of their potential customers.In Japan's response to the coronavirus disease 2019 (COVID-19), virus testing was limited to symptomatic patients due to limited capacity, resulting in uncertainty re

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Colorectal cancer risk in middle-aged Japanese adults was not found to be related to their sugar intake. The potential for an increased risk of rectal cancer in women consuming significant quantities of total sugar cannot be definitively ruled out. Corneal epithelium renewal originates from limbal stem/progenitor cells (LSC). The regulatory mechanisms governing LSC proliferation and differentiation are critical for maintaining corneal homeostasis, but remain large

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[This corrects the article DOI 10.3389/fphys.2019.01432.].Introduction Chronic exposure to the weightlessness-induced cephalad fluid shift is hypothesized to be a primary contributor to the development of spaceflight-associated neuro-ocular syndrome (SANS) and may be associated with an increased risk of venous thrombosis in the jugular vein. This study characterized the relationship between gravitational level (Gz-level) and acute vascular changes. Methods Internal jugular vein (IJV) cross-sectional area, inferior ve

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Recurrent pregnancy loss (RPL) is defined as the loss of two or more pregnancies and is often multifactorial with the majority of miscarriages being due to aneuploidy and anatomic or physiological abnormalities. However, inherited or acquired thrombophilias have also been associated with RPL, albeit inconsistently. While inherited thrombophilias, such as factor V Leiden and prothrombin gene mutation, are relatively prevalent in women with RPL compared with the general population, a causal link has yet to be definitively established. Recen

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