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Oxygen is a pulmonary vasodilator and plays an important role in mediating circulatory transition from fetal to postnatal period. Oxygen tension (PO2) in the alveolus (PAO2) and pulmonary artery (PaO2) are the main factors that influence hypoxic pulmonary vasoconstriction (HPV). Inability to achieve adequate pulmonary vasodilation at birth leads to persistent pulmonary hypertension of the newborn (PPHN). Supplemental oxygen therapy is the mainstay of PPHN management. However, optimal monitoring and targeting of oxygenation to achieve

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Finally, general principles for the modification of the MOF electronic structure are formulated and the routes to achieve an appropriate band alignment with carrier-transporting materials, co-catalysts, and redox reaction potentials are suggested.The structure of 2,4-(4'-aminobenzenamine)pyrimidine (1), a pyrimidine alkaloid previously isolated from the bulbs of Scilla madeirensis (Asparagaceae, synonym Autonoë madeirensis), has been revised. These conclusions were met via comparison of reported NMR and EIMS data with those obt

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Results The AUC of the RM [0.81 (95% CI, 0.771-0.848); sensitivity 0.794; specificity 0.704] for the predictive performance of pN1 and N2 was significantly better than that of cN in the training cohort [0.685 (95% CI, 0.644-0.728); sensitivity 0.804; specificity 0.568], (P-value = 8.29e-07, as assessed by the Delong test). In the testing cohort, the AUC of the RM [0.766 (95% CI, 0.702-0.83; sensitivity 0.688; specificity 0.704] was also significantly higher than that of cN [0.685 (95% CI, 0.619-0.747); sensitivity 0.799; specificity 0

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Wiley Sons Ltd.Selective cleavage of the β-O-4 ether bond of lignin to produce aromatics is one of the most important topics for the sustainable production of chemicals from biomass. A simple system has been developed for Cα -Cβ bond cleavage of a β-O-4 ketone-structured lignin model compound (LMC) by H2 O2 in formic acid under metal catalyst-free conditions. By using this simple system, with H2 O2 , formic acid, and mineral acid catalyst, over 90 % product yield is achieved in 6 h at room temperature. The reaction proce

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4 [95% CI 7.9, 16.9; 0.001; standardized effect size by Cohen's 0.93]; mean change in Social Function score was +7.9 (95% CI 3.3, 12.5; = 0.001; effect size 0.5; and mean change in Appearance-related Psychosocial Distress score was -20.9 (95% CI -27.4, -14.3; 0.001; effect size 1.27). Aesthetic treatment with injectables was associated with significant improvements in patient-reported psychological and social functioning and reductions in appearance-related distress. This change underlines the value of these therapies for im

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Human mesenchymal stem cells (MSCs), a promising source of stem cells for regenerative medicine, have different morphological and functional characteristics. Carbohydrate moieties on the cell surface play an important role, including cell-cell interaction and cell recognition. The objective of this study was to determine possible differences in glycoconjugate distribution patterns of MSCs derived from various sources. MSCs were isolated from adipose tissue, bone marrow, Wharton's jelly, and cord blood. Then, they were stained with FITC-c