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The results indicate that the machine learning approaches are more stable, predictable, and suitable for CMGs when a high-accuracy analysis is required. In summary, NIR spectroscopy coupled with machine learning techniques is a suitable tool for the straightforward quantification of CMGs.The cells of the immune and neuronal systems share different receptors for cytokines or neurotransmitters, producing feedback responses between both systems. Cytokines such as IL-1β and TNF-α can induce inflammation; however, the secretion of these mole