https://www.selleckchem.com/pr....oducts/epz004777.htm
Chronic kidney disease is a common comorbidity among patients taking direct-acting oral anticoagulants (DOACs). #link# Herein, we evaluate the influence of kidney function on stroke or systemic embolism (SEE), hemorrhage, and composite end points (stroke/SEE/hemorrhage/death and stroke/SEE/death) among patients on DOACs and warfarin. Baseline kidney function was categorized as glomerular filtration rate (GFR) ≥ 60 (reference), 45-59, and less then 45mL/min/1.73 m2 for participants in the Randomized Evaluation of Long-Term Anticoagulan