https://www.selleckchem.com/pr....oducts/geneticin-g41
001). Serum urea, creatinine, albumin was significantly ameliorated by (p0.001). It was shown the significantly decrease the kidney expression CTGF and RAGE genes and MDA level and increased the SOD activity (p0.001). Also, it was found that the beneficial effects of the were dose-dependent (p0.05). The results of this study suggest that as an adjunct therapy may prevent development and treatment of diabetic nephropathy by regulating the expression of the CTGF and RAGE genes and oxidative stress. The results o