https://www.selleckchem.com/pr....oducts/n-ethylmaleim
Viruses utilize cellular lipids and manipulate host lipid metabolism to ensure their ****tion and spread. Therefore, the identification of lipids and metabolic pathways that are suitable targets for antiviral development is crucial. Using a library of compounds targeting host lipid metabolic factors and testing them for their ability to block pseudorabies virus (PRV) and vesicular stomatitis virus (VSV) infection, we found that U18666A, a specific inhibitor of Niemann-Pick C1 (NPC1), is highly potent in suppressing the e