https://en4inhibitor.com/a-man....uscript-distributed-
This study explored EZH2 expression modulation using CRISPR/Cas9-mediated gene editing and pharmacological inhibition by EZH2 inhibitor EPZ6438, alone or in combination with MAPK inhibitor U0126. In vitro studies revealed that CRISPR/Cas9-mediated EZH2 gene editing effectively curbed cell growth, migration, and invasiveness, and translating to a 90% reduction in tumor growth when EZH2-modified cells were tr
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