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The manual monitoring of young infants suffering from diseases like reflux is significant, since infants can hardly articulate their feelings. In this work, we propose a video-based infant monitoring system for the analysis of infant expressions and states, approaching real-time performance. The expressions of interest consist of discomfort, unhappy, joy and neutral, whereas states include sleep, pacifier and open mouth. Benefiting from the expression analysis, the discomfort moments can also be used and correlated with a symptom-relate