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This research's results can be theoretically applied to understanding how quinoa reacts to high-temperature stress, and to isolating genes and strains exhibiting resilience to high temperatures. The study uncovers how the HSF transcription factor family and purinergic pathway respond to high heat stress, thereby improving the heat resilience of quinoa. Quinoa's adaptation to high-temperature stress involves the regulation of the HSF transcription factor family and the purinergic pathw