https://www.selleckchem.com/pr....oducts/lonafarnib-sc
Electrophysiological experiments characterized the effects of β-AR ligands on striatal ChIs. LID was observed in a subset of DA-deficient mice. Treatment with propranolol relieved LID and motor hyperactivity. Electrophysiological experiments showed that β-ARs can effectively modulate ChI firing. The work suggests that pharmacological modulation of ChIs by β-ARs might provide a therapeutic option for managing LID. The work suggests that pharmacological modulation of ChIs by β-ARs might provide a therapeutic option for managin