https://monastrolinhibitor.com..../learning-the-proble
Models of hepatocellular carcinoma (HCC) were developed, including PDTX models from three patients and orthotopic models using HepG2 cells. In preclinical studies using tumor xenograft models, mice received AST-3424 alone or in combination with oxaliplatin, apatinib, sorafenib, and elemene. Alternatively, in orthotopic models, oxaliplatin and 5-fluorouracil were administered along with AST-3424. The evaluation protocol included assessment of the mice's weig
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