https://www.selleckchem.com/pr....oducts/gc376-sodium.
© 2019 The Authors. Published by WILEY‐VCH Verlag GmbH Co. KGaA, Weinheim.The use of opioids in chronic non-cancer pain (CNCP) has been a fast-rising treatment phenomenon in the last two decades. Though opioids are advocated in various chronic pain management guidelines, their use in chronic non-cancer pain still remains controversial as evidence of this approach is still weak. This paper highlights potential adverse effects associated with opioid use in pain management, including an increase in tolerance, dependence, and add
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