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OBJECTIVE To design and validate the second edition of the Female Sexual Function questionnaire (FSF-2). MATERIAL AND METHODS A cross-sectional and multicentre study was conducted on 187 women (18-70 years) who completed a test (preliminary questionnaire FSF-2), and then answered a structured anamnesis on female ****ual function. Four weeks later they completed a retest, which was equal to the test but with an additional question about possible influence of recent events in their **** life. RESULTS The mean age of the women was 43.51 yea