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CONCLUSIONS To address these findings, we suggest methods to improve ****ual education, combat male infidelity, promote condom use, and improve health services to reduce the incidence of STIs in Maya Guatemala.BACKGROUND Synthetic particulate hydroxyapatite (HAP; Ca5(PO4)3(OH)) is used as ingredient in oral care products but its effects on cariogenic biofilms are not clear yet. The primary mode of action of HAP may be acting as a calcium phosphate reservoir when deposited in oral biofilms and release Ca2+ and (hydrogen) phosphate ions upon