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RESULTS After 6 weeks, DOSS scores improved in patients in all 3 groups, and there were significant differences among the groups in their scores (P less then 0.001 for both measures). In the CT and ET groups, there was a statistically significant difference in the number of patients with SAP before and after treatment (P=0.010 and P less then 0.001, respectively). There also were fewer cases in the IST group than in the CT (P=0.042) and ET groups (P=0.011). After completion of treatment, compared with the first treatment, there were sign