https://www.selleckchem.com/pr....oducts/hexa-d-argini
Incapacitance data showed that CPZ significantly reduced DMM-induced pain in male mice but not in female mice. Immunofluorescence microscopy analysis demonstrated that DMM surgery increased the expression of TRPV1 in both female and male dorsal root ganglion (DRG). Injection of CPZ significantly suppressed TRPV1 expression in the DRG of male mice only. Joint damage develops comparably in both female and male mice after DMM although it progresses less in females. There was a subtle **** difference in pain behaviors and analgesic e