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Moreover, the effect of Fst is to block the Activin-Nodal signaling pathway in the forebrain, thereby impeding Nodal activation before the arrival of Spaw from the left lateral periventricular migratory stream at a later time. This contribution directly impacts the organized progression of asymmetric Nodal activation, which occurs along the PA axis. The observed effect of Fst's LR regulatory function is further validated in both chick and frog em
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