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duction of the intrinsic host cellular response. To circumvent these defenses, these viruses form tightly regulated ribonucleoprotein ****tion complexes in order to protect their genomes from detection and to prevent excessive aberrant ****tion. Here, we demonstrate the balance that negative-sense RNA viruses must achieve both to ****te efficiently and to avoid induction of the host defenses.Porcine epidemic diarrhea virus (PEDV) is an α-coronavirus causing severe diarrhea and high mortality rates in suckling piglets and posin